What sources are included in the Kratom Research Library?

The library includes 201+ sources including peer-reviewed pharmacology studies, FDA regulatory documents, DEA statements, toxicology reports, clinical case studies, court records, mortality data, and industry analysis from government agencies, academic institutions, and medical journals.

Is kratom safe according to scientific research?

Scientific research documents significant safety concerns including opioid-like dependence, withdrawal symptoms, toxicity from alkaloids like 7-hydroxymitragynine, deaths involving kratom (both alone and in combination with other substances), and widespread product adulteration with heavy metals, salmonella, and undisclosed synthetic opioids.

What does research say about kratom's pharmacology?

Research shows kratom's primary alkaloids (mitragynine and 7-hydroxymitragynine) activate mu-opioid receptors, produce respiratory depression at high doses, cause physical dependence, and have abuse liability. Studies document complex pharmacology affecting multiple neurotransmitter systems beyond opioid receptors.

What regulatory actions have been taken on kratom?

The FDA has issued import alerts, mandatory recalls, public health advisories, and documented kratom's association with deaths. The DEA listed kratom as a Drug and Chemical of Concern. Multiple countries have scheduled kratom as a controlled substance. The FDA has never approved kratom for any medical use.

Evidence Database

Master Research Library

200+ peer-reviewed studies, government documents, and primary sources with full citations and cross-references to investigation articles

259

Total Sources

112

Peer-Reviewed Studies

Government Documents

Industry & Legal Records

Showing 259 sources